Signatures of early frailty in the gut microbiota

Jackson M, Jeffery IB, Beaumont M, et al. Genome Med 2016;8:8. Publication date: January 29, 2016 Summary Frailty is arguably the biggest problem associated with population ageing. Jackson et al. aimed to characterize frailty associations with the gut microbiota in a...

The cost of frailty in France

Sirven N, Rapp T Eur J Health Econ 2016; Feb 25 Publication date: February 25, 2016 Summary The objective of the present work was to explore the incremental costs of frailty associated with ambulatory health care expenditures (HCE) among the French population of...

Depression and frailty in later life: a systematic review

Vaughan L, Corbin AL, Goveas JS Clin Interv Aging 2015;10:1947-58 Publication date: December 15, 2015 Summary Frailty and depression are important issues affecting older adults. Depressive syndrome may be difficult to clinically disambiguate from frailty in advanced...

Nutrition, frailty and prevention of disabilities with aging

Guyonnet S, Secher M, Ghisolfi A, Ritz P, Vellas B J Frailty Aging 2013;4:13-25 Publication date: March 1, 2015 Summary The heterogeneous group of older adults may be differentiated into three subgroups in order to facilitate the development and implementation of...

Community-based intervention for prevention of dementia in Japan

Suzuki T, Makizako H, Doi T, et al. J Prev Alz Dis 2015;2:71-76 Publication date: March 1, 2015 Summary Population aging is accelerating, with prolonged life expectancy and a decrease in birth rate. As age is a significant risk factor for dementia, we are confronted...

Frailty screening in the community using the FRAIL scale

Woo J, Yu R, Wong M, Yeung F, Lum C J Am Med Dir Assoc 2015; Feb 24 [Epub ahead of print] Publication date: February 24, 2015 Summary This study evaluated the feasibility of using the FRAIL scale in community screening of older Chinese people aged 65 years and older,...

Cognitive function in the prefrailty and frailty syndrome

Robertson DA, Savva GM, Coen RF, Kenny RA J Am Geriatr Soc 2014;62:2118-2124 Publication date: November 1, 2014 Summary The objective of this study by Robertson et al. was to explore the relationship between cognitive function and frailty. Individuals aged 50 and...

Adverse outcomes of frailty in the elderly: the Rotterdam Study

Lahousse L, Maes B, Ziere G, et al. Eur J Epidemiol 2014;29:419-27 Publication date: June 1, 2014 Summary Given the expanding elderly population and the major impact of population aging on health and social care, the identification of frail people among older adults...

Frailty and hip osteoarthritis in men in the MrOS cohort

Wise BL, Parimi N, Zhang Y, et al. J Gerontol A Biol Sci Med Sci 2014;69:602-8. Publication date: May 1, 2014 Summary This is a longitudinal cohort study of men aged more than 65 years in the Osteoporotic Fractures in Men Study, examining the association of hip...

Fish oils and their potential in the treatment of sarcopenia

Gray SR, Da Boit M J Frailty Aging 2013;2:205-10 Publication date: December 1, 2013 Summary There are several nutritional strategies purported to be useful in the treatment of sarcopenia. In recent years, the n-3 polyunsaturated fatty acids (PUFAs) found in fish oil...

The cognitive impairment of frail older persons

Cesari M, Andrieu S, Rolland Y, Nourhashemi F, Vellas B J Nutr Health Aging 2013;17:735-7 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of...

Cognitive frailty

Buchman AS, Bennett DA J Nutr Health Aging 2013;17:738-9 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of the Journal of Nutrition, Health...

Cognitive frailty: frontiers and challenges

Woods AJ, Cohen RA, Pahor M J Nutr Health Aging 2013;17:741-3 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of theJournal of Nutrition, Health...

Incorporating frailty into clinical practice and clinical research

Rowe JW, Fried LP J Frailty Aging 2013;2:126-7 Publication date: September 1, 2013 Summary In the context of a rapidly growing interest in frailty, the authors identify several valuable strategies for inclusion of special attention to the syndrome in the clinical care...

The stress of aging

Cesari M, Vellas B, Gambassi G Exp Gerontol 2013;48:451-6 Publication date: April 1, 2013 Summary While biological and evolutionary ageing theories have been analysed for centuries, our current knowledge of how we age remains incomplete. In this article, the authors...

Frailty in elderly people

Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K Lancet 2013;381:752-62 Publication date: March 2, 2013 Summary The healthcare systems of today are characterized primarily by single-system illnesses, despite the fact that many elderly people have multi-organ...

Sarcopenia: the target population

Malmstrom T, Morley J J Frailty Aging 2013;2:55-6 Publication date: March 1, 2013 Summary This article reports on a presentation by Malmstrom and Morley at the December 2012 meeting of the International Task Force on Sarcopenia in Orlando, Florida, USA. In their...

Implementing frailty into clinical practice: we cannot wait

Implementing frailty into clinical practice: we cannot wait Vellas B, Cestac P, Moley JE J Nutr Health Aging 2012;16:599-600. Publication date: August 1, 2012 Summary Since the 1980s, geriatric medicine has expanded to the point that there are acute care units, mobile...

How to include the social factor for determining frailty?

Gutiérrez-Robledo LM, Avila-Funes JA J Frailty Aging 2012;1:13-7 Publication date: March 1, 2012 Summary Research on the determinants of adult and old-adult health recognizes the need to incorporate earlier life circumstances, including education, economic status,...