Suzuki T, Makizako H, Doi T, et al.

J Prev Alz Dis 2015;2:71-76

Publication date: March 1, 2015


Population aging is accelerating, with prolonged life expectancy and a decrease in birth rate. As age is a significant risk factor for dementia, we are confronted with an ever-increasing prevalence of mild cognitive impairment (MCI)/dementia. Thus, the Japanese National Center for Geriatrics and Gerontology launched a project to promote community-based research, including the development of an effective screening system for high-risk groups and intervention for dementia prevention.

This review introduces the project, the Obu Study of Health Promotion for the Elderly, with the following strategic triad:

  1. Identification of the target population by population screening; we regarded patients with MCI as the target population, and developed a screening test battery to identify MCI in a population screening setting.
  2. Scientific evaluation of community-based intervention; the authors developed an interventional method combining exercise and cognitive training (“cognicise”). In practical settings, “cognicise” is programmed into multicomponent exercise intervention, which was reported to have benefits of cognitive improvement and reduction of brain atrophy based on randomized controlled trials.
  3. Standardization of the methods of population screening and community-based intervention for evidence-based policy making and widespread implementation.

Dementia prevention, or at least delaying the onset of dementia and/or stopping/slowing the progression of dementia, should benefit the whole society as well as individuals. It is a continuing challenge to improve the screening system and community-based intervention for dementia prevention through accumulation of evidence.

Journal Website