Leong DP, Teo KK, Rangarajan S, et al. Lancet 2015;386:266-273 Publication date: July 18, 2015 Summary Reduced muscular strength, as measured by grip strength, has been associated with an increased risk of all-cause and cardiovascular mortality. Grip strength is a...
Gill TM, Gahbauer EA, Han L, Allore HG BMJ 2015;350:h2361 Publication date: June 20, 2015 Commentary: Acute Hospital Admissions Influence the Disabling Process in the Last Year of Life Reviewer: Jun Li Institut du Vieillissement, Gérontopôle, Université Toulouse III –...
Parentoni AN, Mendonça VA, Dos Santos KD, Sa LF, Ferreira FO, Gomes Pereira DA, Lustosa LP J Frailty Aging 2015;4(2):64-68 Publication date: June 1, 2015 Summary Gait speed is considered a predictor of adverse health outcomes and functional decline in older persons....
Chen S, Honda T, Chen T, et al. BMC Geriatr 2015;15:36 Publication date: April 2, 2015 Summary The increasing incidence and prevalence of frailty due to population aging poses a great challenge to public healthcare and social care systems as demands for medical and...
Halil M, Cemal Kizilarslanoglu M, Emin Kuyumcu M, Yesil Y, Cruz Jentoft AJ J Nutr Health Aging 2015;19:276-283 Publication date: March 1, 2015 Summary Whereas physical impairment is the main hallmark of frailty, evidence suggests that other dimensions, such as...
Pabst G, Zimmermann AK, Huth C, et al. J Nutr Health Aging 2015;19:258-264 Summary Older adults often suffer from vitamin D deficiency and from the frailty syndrome characterized by different physical limitations, complicating independent everyday life. c The authors’...
Kurka JM, Vezina J, Brown DD, Schumacher J, Cullen RW, Laurson KR J Frailty Aging 2013;4:26-33 Publication date: March 1, 2015 Summary Age-related loss of muscle mass and related ailments are of concern due to associations with disabilities and morbidity as well as...
Wen X, An P, Chen WC, Lv Y, Fu Q J Nutr Health Aging 2015;19:342-347 Publication date: March 1, 2015 Summary In this study, Wen et al. investigated prevalence of sarcopenia and the applicability of different diagnostic criteria in 286 Chinese adults (136 men and 150...
Triscott JAC, Dobbs BM, McKay RM, Babenko O, Triscott E J Frailty Aging 2013;4:7-12 Publication date: March 1, 2015 Summary The prevalence of anemia in hospitalized seniors has been linked to poor functional outcomes, increased mortality, and longer hospital stays,...
Guyonnet S, Secher M, Ghisolfi A, Ritz P, Vellas B J Frailty Aging 2013;4:13-25 Publication date: March 1, 2015 Summary The heterogeneous group of older adults may be differentiated into three subgroups in order to facilitate the development and implementation of...
Abner EL, Kryscio RJ, Caban-Holt A, Schmitt FA J Prev Alz Dis 2013;2:11-16 Publication date: March 1, 2015 Summary Subjective memory complaints reflect patient-identified deficits in memory and have been linked to increased risk of future dementia in non-demented...
Crichton GE, Elias MF, Davey A, Alkerwi A, Dore GA J Prev Alz Dis 2015;2:24-32 Publication date: March 1, 2015 Summary Few studies have examined whether cognitive function predicts dietary intake. The majority of research has focused on how diet can influence...
Barnett JC, Bahar-Fuchs A, Cherbuin N, Herath P, Anstey KJ J Prev Alz Dis 2015;2:38-45 Publication date: March 1, 2015 Summary Without preventative strategies, the burden of dementia is likely to increase rapidly worldwide. Primary prevention approaches involve...
de Souto Barreto P, Vellas B, Andrieu S, Rolland Y J Prev Alz Dis 2015;2:56-63 Publication date: March 1, 2015 Summary Physical activity (PA) contributes to brain health and plasticity, which suggests that PA would protect against the development of Alzheimer’s...
Suzuki T, Makizako H, Doi T, et al. J Prev Alz Dis 2015;2:71-76 Publication date: March 1, 2015 Summary Population aging is accelerating, with prolonged life expectancy and a decrease in birth rate. As age is a significant risk factor for dementia, we are confronted...
Woo J, Yu R, Wong M, Yeung F, Lum C J Am Med Dir Assoc 2015; Feb 24 [Epub ahead of print] Publication date: February 24, 2015 Summary This study evaluated the feasibility of using the FRAIL scale in community screening of older Chinese people aged 65 years and older,...
Blodgett J, Theou O, Kirkland S, Andreou P, Rockwood K Maturitas 2015;80:187-91 Publication date: February 1, 2015 Summary The objective of this study was to examine how high levels of sedentary behavior and low levels of activity are associated with increased frailty...
Reisinger KW, van Vugt JL, Tegels JJ, et al. Ann Surg 2015;261:345-52 Publication date: February 1, 2015 Summary This study was aimed at determining the association of sarcopenia with postoperative morbidity and mortality after colorectal surgery. A total of 310...
Gale CR, Cooper C, Sayer AA Age Ageing 2015;44:162-165 Publication date: January 1, 2015 Summary In this study, the authors examined the prevalence of frailty and disability among 5,450 individuals aged 60 and over from the English Longitudinal Study of Ageing, as...
Zisberg A, Shadmi E, Gur-Yaish N, Tonkikh O, Sinoff G J Am Geriatr Soc 2015;63:55-62 Publication date: January 1, 2015 Summary Hospitalizations often lead to functional loss in older people. There are many factors (e.g. patient characteristics) that may explain this...
Romero-Ortuno R, Soraghan C BMJ Open 2014;4:e006645 Publication date: December 23, 2014 Summary The objective of the present study was to create and validate a frailty assessment tool for community-dwelling adults aged ≥75 years. It is a Longitudinal, population-based...
Dapp U, Minder CE, Anders J, Golgert S, von Renteln-Kruse W BMC Geriatr 2014;14:141 Publication date: December 19, 2014 Summary The detection of functional decline in elderly persons is not an easy task. Dapp et al. suggest that the self-reporting Functional Ability...
Mijnarends DM, Schols JM, Meijers JM, et al. J Am Med Dir Assoc 2014; Dec 17 [Epub ahead of print] Publication date: December 17, 2014 Summary Both sarcopenia and physical frailty are geriatric syndromes causing loss of functionality and independence. Mijnarends et...
Syddall HE, Westbury LD, Cooper C, Sayer AA J Am Med Dir Assoc 2014; Dec 15 [Epub ahead of print] Publication date: December 15, 2014 Summary Walking speed is central to emerging consensus definitions of sarcopenia and frailty; it is also a major predictor of future...
Kumar R, Mohan N, Upadhyay AD, et al. Aging Cell 2014;13:975-80 Publication date: December 1, 2014 Summary Manifestations of frailty include sarcopenia (loss of skeletal muscle mass), cognitive decline, abnormal functioning of immune and neuroendocrine systems, and...
Forti P, Maioli F, Zagni E, et al. J Nutr Health Aging 2014;18:912-8 Publication date: December 1, 2014 Summary The objective of this study was to determine the usefulness of physical phenotype of frailty, cognitive impairment and serum albumin for risk stratification...
Kim S, Park JL, Hwang HS, Kim YP Korean J Fam Med 2014;35:309-320 Publication date: November 1, 2014 Summary Frailty and cognitive impairment are considered the most common and yet the least well understood conditions in older adults. This study was conducted to...
Romera L, Orfila F, Segura JM, et al. BMC Geriatr 2014;14:125 Publication date: November 27, 2014 Summary Frailty is a highly prevalent condition in old age leading to vulnerability and greater risk of adverse health outcomes and disability. Detecting and tackling...
Robertson DA, Savva GM, Coen RF, Kenny RA J Am Geriatr Soc 2014;62:2118-2124 Publication date: November 1, 2014 Summary The objective of this study by Robertson et al. was to explore the relationship between cognitive function and frailty. Individuals aged 50 and...
Oubaya N, Mahmoudi R, Jolly D, et al. J Nutr Health Aging 2014;18:757-64 Publication date: August 1, 2014 Summary The objective of this study by Oubaya et al. was to validate the modified version of the Short Emergency Geriatric Assessment (SEGAm) frailty instrument...
Cesari M, Demougeot L, Boccalon H, et al. PLoS One 2014;9:e101745 Publication date: July 7, 2014 Summary The detection of frail older individuals living in the community represents a crucial preliminary step in the development of effective prevention against...
Joseph B, Pandit V, Zangbar B, et al. J Am Coll Surg 2014;219:10-7.e1 Publication date: July 1, 2014 Summary Early prediction of discharge disposition is an important component in the management of trauma patients. The authors have previously demonstrated that frailty...
May 5, 2014 Discover the highlights of the 2014 International Conference on Frailty and Sarcopenia Research that took place in Barcelona on March 12-14, 2014, as well as the announcement of next year’s conference, in this special edition of the Frailty newsletter....
March 14, 2014 Barcelona, Spain, March 14, 2014 – Declining muscle mass and strength in the elderly are major contributors to both physical and cognitive disability and thus, loss of independence. Since both physical inactivity and inadequate protein intake have been...
March 14, 2014 Barcelona, Spain, March 14, 2014 – Seeking innovative approaches to combat the devastating effects of frailty and muscle loss in the older person, the Innovative Medicines Initiative Joint Undertaking (IMI-JU) will soon announce the project finally...
March 13, 2014 Barcelona, Spain, March 13, 2014 – A new drug being developed for the treatment of a rare muscle wasting disease called sporadic inclusion body myositis (sIBM), and which is being investigated in sarcopenia in elderly patients, has also been shown to...
March 12, 2014 Barcelona, Spain, March 12, 2014 – Physical frailty, which has been linked to a reduced ability to fend off disability in old age, is also associated with increased levels of cognitive impairment, according to research presented today at the...
March 10, 2014 What is Frailty & Sarcopenia? Frailty is a clinical syndrome in which there is an increase in an individual’s vulnerability for developing increased dependency due to three or more of the following criteria: unintentional weight loss, self-reported...
Dent E, Chapman I, Howell S, Piantadosi C, Visvanathan R Age Ageing 2014;43:477-84 Publication date: July 1, 2014 Summary This is a prospective, observational study in patients aged ≥ 70 years admitted to a Geriatric Evaluation and Management Unit (GEMU) in Australia,...
Kim SW, Han HS, Jung HW, et al. JAMA Surg 2014;149:633-40 Publication date: July 1, 2014 Summary The number of older patients who undergo surgery is increasing, and these patients often have comorbid conditions that may lead to postoperative mortality and morbidity....
Ferguson MK, Thompson K, Huisingh-Scheetz M, et al. PLoS One 2014;9:e98654 Publication date: June 3, 2014 Summary Frailty is a predictor of poor outcomes following many types of operations. Ferguson et al. measured thoracic surgeons’ accuracy in assessing...
Lahousse L, Maes B, Ziere G, et al. Eur J Epidemiol 2014;29:419-27 Publication date: June 1, 2014 Summary Given the expanding elderly population and the major impact of population aging on health and social care, the identification of frail people among older adults...
Wise BL, Parimi N, Zhang Y, et al. J Gerontol A Biol Sci Med Sci 2014;69:602-8. Publication date: May 1, 2014 Summary This is a longitudinal cohort study of men aged more than 65 years in the Osteoporotic Fractures in Men Study, examining the association of hip...
Rojas-Fernandez CH, Patel T, Lee L Ann Pharmacother 2014;48:785-95 Publication date: June 1, 2014 Summary The purpose of this article is to describe the role of clinical pharmacists providing care to patients with cognitive complaints in a primary care-based,...
Greene BR, Doheny EP, O’Halloran A, Anne Kenny R Age Ageing 2014;43:406-11 Publication date: May 1, 2014 Summary The concept of frailty in older adults has emerged as an important geriatric syndrome. It is a multi-factorial condition, influenced by the combination of...
Tavassoli N, Guyonnet S, Abellan Van Kan G, et al. J Nutr Health Aging 2014;18:457-64 Publication date: May 1, 2014 Summary The authors report on the first two years of operation of the Geriatric Frailty Clinic for Assessment of Frailty and Prevention of Disability...
Dorner TE, Luger E, Tschinderle J, et al. J Nutr Health Aging 2014;18:264-9 Publication date: March 1, 2014 Summary The authors explored the association between the impaired nutritional status and frailty in acute hospitalized elderly patients by using the MNA®-SF...
Bagshaw SM, Stelfox HT, McDermid RC, et al. CMAJ 2014;186:E95-102 Publication date: February 4, 2014 Summary Frailty has not been evaluated in critically ill patients. The development of critical illness may lead to frailty in vulnerable patients, and critical illness...
van Kempen JA, Schers HJ, Melis RJ, Olde Rikkert MG J Clin Epidemiol 2014;67:176-83. Publication date: February 1, 2014 Summary The EASY-Care Two-step Older persons Screening (EASY-Care TOS) tool is a practice-based tool designed to help family physicians identify...
Gray SR, Da Boit M J Frailty Aging 2013;2:205-10 Publication date: December 1, 2013 Summary There are several nutritional strategies purported to be useful in the treatment of sarcopenia. In recent years, the n-3 polyunsaturated fatty acids (PUFAs) found in fish oil...
Lacey LA, Niecko T, Leibman C, Liu E, Grundman M J Nutr Health Aging 2013;17:745-50. Publication date: November 1, 2013 Summary In patients with Alzheimer’s disease (AD), dependence has been shown to correlate with impairments in cognition, function and behaviour. In...
Malmstrom TK, Morley JE J Nutr Health Aging 2013;17:723-5 Publication date: November 1, 2013 Summary In this editorial, the authors comment on a consensus statement published in the September 2013 of the Journal of Nutrition, Health & Aging. Physical frailty has...
Cesari M, Andrieu S, Rolland Y, Nourhashemi F, Vellas B J Nutr Health Aging 2013;17:735-7 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of...
Buchman AS, Bennett DA J Nutr Health Aging 2013;17:738-9 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of the Journal of Nutrition, Health...
Woods AJ, Cohen RA, Pahor M J Nutr Health Aging 2013;17:741-3 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of theJournal of Nutrition, Health...
El-Khoury F, Cassou B, Charles MA, Dargent-Molina P BMJ 2013;347:f6234. Publication date: October 29, 2013 Summary Fall-related injuries are very common among older people and are a major cause of long-term pain and functional impairment. They also increase the risk...
Hamaker ME, Jonker JM, de Rooij SE, Vos AG, Smorenburg CH, van Munster BC Lancet Oncol 2012;13:e437-44 Publication date: October 1, 2013 Summary In older patients with cancer, pre-screening may be used to identify fit patients who are able to receive standard...
Harttgen K, Kowal P, Strulik H, Chatterji S, Vollmer S PLoS One 2013;8:e75847 Publication date: October 29, 2013 Summary Frailty is increasingly common as a result of population aging. Assessing levels of frailty in higher versus lower income countries gives a unique...
Philp IJ Frailty Aging 2013;2:128 Publication date: September 1, 2013 Summary Primary care physicians are well aware of the human and financial consequences of frailty ‒ loss of independence in daily living activities, reduced participation in family and community...
Metzelthin SF, van Rossum E, de Witte LP, et al. BMJ 2013;347:f5264. Publication date: September 12, 2013 Summary In this cluster randomized controlled trial, the authors randomly allocated 12 general practices in the Netherlands to a “Prevention of Care” approach or...
Rowe JW, Fried LP J Frailty Aging 2013;2:126-7 Publication date: September 1, 2013 Summary In the context of a rapidly growing interest in frailty, the authors identify several valuable strategies for inclusion of special attention to the syndrome in the clinical care...
Subra J, Gillette-Guyonnet S, Cesari M, Oustric S, Vellas B J Nutr Health Aging 2012;16:714-20. Publication date: August 1, 2013 Summary Despite growing importance placed on preventing disability, implementation of frailty parameters in the clinical setting is still...
Cesari M, Vellas B, Gambassi G Exp Gerontol 2013;48:451-6 Publication date: April 1, 2013 Summary While biological and evolutionary ageing theories have been analysed for centuries, our current knowledge of how we age remains incomplete. In this article, the authors...
Vellas B, Balardy L, Gillette-Guyonnet S, et al. J Nutr Health Aging 2013;17:629-31 Publication date: July 1, 2013 Summary Identification of frail patients before their vulnerability is made evident by the onset of a major clinical event is one of the major challenges...
Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K Lancet 2013;381:752-62 Publication date: March 2, 2013 Summary The healthcare systems of today are characterized primarily by single-system illnesses, despite the fact that many elderly people have multi-organ...
Malmstrom T, Morley J J Frailty Aging 2013;2:55-6 Publication date: March 1, 2013 Summary This article reports on a presentation by Malmstrom and Morley at the December 2012 meeting of the International Task Force on Sarcopenia in Orlando, Florida, USA. In their...
Favela J, Castro LA, Franco-Marina F, et al. Clin Interv Aging 2013;8:85-95 Publication date: January 1, 2013 Summary The objective of this present study was to assess whether an intervention based on nurse home visits including alert buttons (NV+AB) is effective in...
Calvani R, Miccheli A, Landi F, et al. J Frailty Aging 2013;2:38-53 Publication date: March 1, 2013 Summary Older age is linked with significant changes in body composition, the most notable of which is loss of skeletal muscle, or sarcopenia. Adults over 35 lose...
Morley JE, Malmstrom TK, Miller DK J Nutr Health Aging 2012;16:601-8 Publication date: August 1, 2012 Summary The aim of this longitudinal study was to validate the 5-item FRAIL scale (fatigue, resistance, ambulation, illnesses, and loss of weight) in a representative...
Cesari M, Fielding RA, Pahor M, et al. J Frailty Aging 2012;1:102-10 Publication date: September 1, 2012 Summary In this consensus document, the International Working Group on Sarcopenia discusses the current state of the art in the development of biomarkers to be...
Implementing frailty into clinical practice: we cannot wait Vellas B, Cestac P, Moley JE J Nutr Health Aging 2012;16:599-600. Publication date: August 1, 2012 Summary Since the 1980s, geriatric medicine has expanded to the point that there are acute care units, mobile...
Yamada M, Arai H, Yoshimura K, et al. J Frailty Aging 2012;1:64-70. Publication date: June 1, 2012 Summary Resistance and/or aerobic training have been shown to be important for the prevention and management of sarcopenia in older adults. Similarly, nutritional...
Gait speed: a new “vital sign” for older persons in primary care Subra J, Rougé-Bugeat M-E, Balardy L, et al. J Frailty Aging 2012;1:90-91. Publication date: June 1, 2012 Summary The identification of frailty in clinical practice needs to be promoted, and...
June 23, 2013 During the International Academy on Nutrition and Aging (IANA) meeting on Nutrition and Physical & Cognitive Frailty Including Sarcopenia, held in Seoul, Korea, on June 23, 2013, Tung Wai Auyeung from the Chinese University of Hong Kong presented an...
June 23, 2013 Gobbens et al. performed a study to assess the predictive validity of the eight individual self-reported components of the physical frailty subscale of the Tilburg Frailty Indicator (TFI) [1] for activities of daily living (ADL) and instrumental...
Gutiérrez-Robledo LM, Avila-Funes JA J Frailty Aging 2012;1:13-7 Publication date: March 1, 2012 Summary Research on the determinants of adult and old-adult health recognizes the need to incorporate earlier life circumstances, including education, economic status,...
