Sharing Progress in Cancer Care (SPCC) Taskforce Cancerworld Link to Journal Published October 19, 2020 Frailty.net review by Gérard Bozet, MD Posted November 9, 2020 Awareness of malnutrition and cachexia in cancer patients The urgent need for better recognition of... Rooks D, Swan T, Goswami B et al. JAMA Network Link to Pubmed / Journal Published October 19, 2020 Frailty.net review by Gérard Bozet, MD Posted November 5, 2020 Sarcopenia is an important health concern in elderly adults because it is associated with... Manickam R, Duszka K, Wahli W Int J Mol Sci 2020;21. doi: 10.3390/ijms21218056 Link to Pubmed / Journal Published October 19, 2020 Frailty.net review by Gérard Bozet, MD Posted December 9, 2020 Skeletal muscle wasting occurs in many diseases and during... L Rodriguez-Mañas L, Araujo de Carvalho I, Bhasin S, Bischoff-Ferrari H A, Cesari M, Evans W, Hare J M, Pahor M, Parini A, Rolland Y, Fielding R A, Walston J, Vellas B and the ICSFR Task Force J Frailty Aging Link to Pubmed / Journal Published October 7,... Pegah Golabi, Lynn Gerber, James M Paik, Rati Deshpande, Leyla de Avila, Zobair M Younossi JHEP Rep 2020* Link to Pubmed / Journal Published August 15, 2020 Frailty.net review by Gérard Bozet, MD Physical inactivity and sedentary lifestyle have contributed... Picca A, Calvani R, Cesari M et al. Int J Mol Sci 2020;21 Link to Pubmed / Journal Published October 19, 2020 Frailty.net review by Gérard Bozet, MD Posted December 2, 2020 Physical frailty and sarcopenia is a prototypical geriatric condition characterised... Hewitt J, Carter B, Vilches-Moraga A et al. The Lancet Link to Pubmed / Journal Published June 30, 2020 Frailty.net review by Gérard Bozet, MD Posted November 5, 2020 What do we learn from the COPE study about the effect of frailty on survival in patients... John E. Morley Kamyar Kalantar‐Zadeh Stefan D. Anker Journal of Cachexia, Sarcopenia & Muscle Published June 9, 2020 Summary Coronavirus disease (COVID‐19) has reached pandemic proportions. Two animal studies have shown that coronavirus‐2 causes weight loss in... AlGhatrif M, Cingolani O, Lakatta E JAMA Cardiology Link to Pubmed / Journal Published April 3, 2020 Summary An interesting article by Dr Majd AlGhatrif (National Institute on Aging, National Institutes of Health, USA) in JAMA Cardiology, sheds light on... Kunz R, Minder M Swiss Med Wkly. 2020;150:w20235 Published March 24, 2020 Summary Data from various European countries confirm that while the whole population is at risk from infection with the coronavirus (SARS-CoV-2), older people – often frail and subject to... Marco Pahor, Jack M Guralnik, Stephen D Anton, Walter T Ambrosius, Steven N Blair, Timothy S Church, Mark A Espeland, Roger A Fielding, Thomas M Gill, Nancy W Glynn, Erik J Groessl, Abby C King, Stephen B Kritchevsky, Todd M Manini, Mary M McDermott, Michael E Miller,... Charlotte S, Haddock B, Alcazar J, Noerst T, Hansen OM, Ludvig H, Kamper RS, Schnohr P, Prescott E, Andersen LL, Frandsen U, Aagaard P, Bülow J, Hovind P, Simonsen L JCSM 2019; 10: 1316–1329 Link to Pubmed / Journal Published August 16, 2019 Summary Low... Seppala LJ, van der Velde N, Masud T et al. Drugs Aging 2019;36:299-307 Link to Pubmed / Journal Published October 19, 2020 Frailty.net review by Gérard Bozet, MD Posted December 9, 2020 Falls are a major public health concern in the older population, and... The WHO integrated care for older people (ICOPE) Guidelines on community-level interventions to manage declines in intrinsic capacity providing guidance on evidence-based interventions to manage declines in intrinsic capacity in older age is now available. They cover... Campitelli MA, Bronskill SE, Hogan DB, et al. BMC Geriatr 2016;16:133 Publication date: July 7, 2016 Jul 7 BMC Geriatr 2016;16:133. Campitelli MA, Bronskill SE, Hogan DB, et al. Summary Evaluating different approaches to identifying frail home care clients at risk for... Feng L, Nyunt MS, Gao Q, et al. J Gerontol A Biol Sci Med Sci 2016; Mar 24 [Epub ahead of print] Publication date: March 24, 2016 Summary The independent and combined effects of physical and cognitive domains of frailty in predicting the development of mild cognitive... Murray A, McNeil C, Salarirad S, et al. Arch Gerontol Geriatr 2016;63:49-54 Publication date: March 1, 2016 Summary Brain hyperintensities, detectable with MRI, increase with age. They are associated with a triad of impairment in cognitive ability, depression and... Montero-Odasso MM, Barnes B, Speechley M, et al. J Gerontol A Biol Sci Med Sci 2016; Mar 16 [Epub ahead of print] Publication date: March 16, 2016 Summary Cognitive frailty, defined as the presence of both frailty and cognitive impairment, is proposed as a distinctive... Luger E, Dorner TE, Haider S, Kapan A, Lackinger C, Schindler K J Am Med Dir Assoc 2016;17;671.e9-671.e16 Publication date: July 1, 2016 Summary In this study, Luger et al. examined the effects of a home-based and volunteer-administered physical training and... Jackson M, Jeffery IB, Beaumont M, et al. Genome Med 2016;8:8. Publication date: January 29, 2016 Summary Frailty is arguably the biggest problem associated with population ageing. Jackson et al. aimed to characterize frailty associations with the gut microbiota in a... Hofstede JM, Raijmakers NJ, van der Hoek LS, Francke AL Palliat Med 2016; Jan 26 Publication date: January 26, 2016 Summary Palliative care is rooted in the care for incurably ill cancer patients. Yet today there is a recognized need for palliative care for patients... Sirven N, Rapp T Eur J Health Econ 2016; Feb 25 Publication date: February 25, 2016 Summary The objective of the present work was to explore the incremental costs of frailty associated with ambulatory health care expenditures (HCE) among the French population of... Del Brutto OH, Mera RM, Cagino K, et al. Geriatr Gerontol Int 2016; Jan 21 [Epub ahead of print] Publication date: January 21, 2016 Summary Frailty is a geriatric state of physical vulnerability that might be associated with cognitive decline in the absence of a... Dulac MC, Aubertin-Leheudre M J Frailty Aging 2016;5:3-5 Publication date: March 1, 2016 Summary In order to prevent physical and cognitive frailty adverse effects, frail older adults can practice multimodal physical activity programs (resistance/power, aerobic and... Woodhouse L, Gandhi R, Warden SJ, et al. J Frailty Aging 2016;5:62-70 Publication date: March 1, 2016 Summary Total hip arthroplasty relieves joint pain in patients with end-stage osteoarthritis. However, postoperative muscle atrophy often results in suboptimal lower... Mossello E, Profili F, Di Bari M, et al. Age Ageing 2016; Mar 23 [Epub ahead of print] Publication date: March 23, 2016 (Most recent version: June 22, 2016) Summary Identification of older individuals at risk for health-related adverse outcomes (HRAO) is necessary for... Comans TA, Peel NM, Hubbard RE, et al. Age Ageing 2016; Jan 13 [Epub ahead of print] Publication date: January 13, 2016 Summary Older people are high users of healthcare resources. The objective of the study by Comans et al. was to quantify the impact of frailty on... Siordia C, Nguyen HT J Frailty Aging 2015;4:175-180 Publication date: December 1, 2015 Summary Within the assessment of frailty, self-rated health (SRH) questions remain frequently used in survey research attempting to quantify a subjective and global measure of... Vaughan L, Corbin AL, Goveas JS Clin Interv Aging 2015;10:1947-58 Publication date: December 15, 2015 Summary Frailty and depression are important issues affecting older adults. Depressive syndrome may be difficult to clinically disambiguate from frailty in advanced... Fougère B, Vellas B, Billet S, et al. Ageing Res Rev 2015;24:299-303 Publication date: November 1, 2015 Summary The rapid growth in the number of older adults has many implications for public health, including the need to better understand the risks posed by... Ng TP, Feng L, Nyunt MS, et al. Am J Med 2015;128:1225-1236 e1221 Publication date: November 1, 2015 Summary The objective of the Singapore Frailty Intervention Trial was to assess whether frailty among older individuals is reversible with nutritional, physical or... Becker C, Lord SR, Studenski SA, et al. Lancet Diabetes Endocrinol 2015;3:948-957 Publication date: December 1, 2015 Summary Myostatin inhibits skeletal muscle growth. The humanised monoclonal antibody LY2495655 (LY) binds and neutralises myostatin. Beker et al.aimed... Journal of Frailty and Aging ‒ Volume 4, Issue 3, September 2015 J Frailty Aging 2015;4(3) Publication date: September 1, 2015 The September 2015 issue of the Journal of Frailty and Aging is now available. Topics discussed in this issue include pharmacological... Bauer JM, Verlaan S, Bautmans I, et al. J Am Med Dir Assoc 2015;16:740-747 Publication date: September 1, 2015 Summary Preserving physical mobility, function and independent living is of utmost importance for frail older adults. Sarcopenia, the age-related loss of... Kahlon S, Pederson J, Majumdar SR, et al. CMAJ 2015;187:799-804 Publication date: August 11, 2015 Summary Readmissions after hospital discharge are common and costly, but prediction models are poor at identifying patients at high risk of readmission. This study... Wang YJ, Wang Y, Zhan JK, et al. Int J Endocrinol 2015;2015:482940 Publication date: July 27, 2015 Summary The aim of this study by Wang et al. was to estimate the prevalence of sarco-osteoporosis and investigate its relationship with frailty in a sample of 316... Leong DP, Teo KK, Rangarajan S, et al. Lancet 2015;386:266-273 Publication date: July 18, 2015 Summary Reduced muscular strength, as measured by grip strength, has been associated with an increased risk of all-cause and cardiovascular mortality. Grip strength is a... Gill TM, Gahbauer EA, Han L, Allore HG BMJ 2015;350:h2361 Publication date: June 20, 2015 Commentary: Acute Hospital Admissions Influence the Disabling Process in the Last Year of Life Reviewer: Jun Li Institut du Vieillissement, Gérontopôle, Université Toulouse III –... Parentoni AN, Mendonça VA, Dos Santos KD, Sa LF, Ferreira FO, Gomes Pereira DA, Lustosa LP J Frailty Aging 2015;4(2):64-68 Publication date: June 1, 2015 Summary Gait speed is considered a predictor of adverse health outcomes and functional decline in older persons.... Chen S, Honda T, Chen T, et al. BMC Geriatr 2015;15:36 Publication date: April 2, 2015 Summary The increasing incidence and prevalence of frailty due to population aging poses a great challenge to public healthcare and social care systems as demands for medical and... Halil M, Cemal Kizilarslanoglu M, Emin Kuyumcu M, Yesil Y, Cruz Jentoft AJ J Nutr Health Aging 2015;19:276-283 Publication date: March 1, 2015 Summary Whereas physical impairment is the main hallmark of frailty, evidence suggests that other dimensions, such as... Pabst G, Zimmermann AK, Huth C, et al. J Nutr Health Aging 2015;19:258-264 Summary Older adults often suffer from vitamin D deficiency and from the frailty syndrome characterized by different physical limitations, complicating independent everyday life. c The authors’... Kurka JM, Vezina J, Brown DD, Schumacher J, Cullen RW, Laurson KR J Frailty Aging 2013;4:26-33 Publication date: March 1, 2015 Summary Age-related loss of muscle mass and related ailments are of concern due to associations with disabilities and morbidity as well as... Wen X, An P, Chen WC, Lv Y, Fu Q J Nutr Health Aging 2015;19:342-347 Publication date: March 1, 2015 Summary In this study, Wen et al. investigated prevalence of sarcopenia and the applicability of different diagnostic criteria in 286 Chinese adults (136 men and 150... Triscott JAC, Dobbs BM, McKay RM, Babenko O, Triscott E J Frailty Aging 2013;4:7-12 Publication date: March 1, 2015 Summary The prevalence of anemia in hospitalized seniors has been linked to poor functional outcomes, increased mortality, and longer hospital stays,... Guyonnet S, Secher M, Ghisolfi A, Ritz P, Vellas B J Frailty Aging 2013;4:13-25 Publication date: March 1, 2015 Summary The heterogeneous group of older adults may be differentiated into three subgroups in order to facilitate the development and implementation of... Abner EL, Kryscio RJ, Caban-Holt A, Schmitt FA J Prev Alz Dis 2013;2:11-16 Publication date: March 1, 2015 Summary Subjective memory complaints reflect patient-identified deficits in memory and have been linked to increased risk of future dementia in non-demented... Crichton GE, Elias MF, Davey A, Alkerwi A, Dore GA J Prev Alz Dis 2015;2:24-32 Publication date: March 1, 2015 Summary Few studies have examined whether cognitive function predicts dietary intake. The majority of research has focused on how diet can influence... Barnett JC, Bahar-Fuchs A, Cherbuin N, Herath P, Anstey KJ J Prev Alz Dis 2015;2:38-45 Publication date: March 1, 2015 Summary Without preventative strategies, the burden of dementia is likely to increase rapidly worldwide. Primary prevention approaches involve... de Souto Barreto P, Vellas B, Andrieu S, Rolland Y J Prev Alz Dis 2015;2:56-63 Publication date: March 1, 2015 Summary Physical activity (PA) contributes to brain health and plasticity, which suggests that PA would protect against the development of Alzheimer’s... Suzuki T, Makizako H, Doi T, et al. J Prev Alz Dis 2015;2:71-76 Publication date: March 1, 2015 Summary Population aging is accelerating, with prolonged life expectancy and a decrease in birth rate. As age is a significant risk factor for dementia, we are confronted... Woo J, Yu R, Wong M, Yeung F, Lum C J Am Med Dir Assoc 2015; Feb 24 [Epub ahead of print] Publication date: February 24, 2015 Summary This study evaluated the feasibility of using the FRAIL scale in community screening of older Chinese people aged 65 years and older,... Blodgett J, Theou O, Kirkland S, Andreou P, Rockwood K Maturitas 2015;80:187-91 Publication date: February 1, 2015 Summary The objective of this study was to examine how high levels of sedentary behavior and low levels of activity are associated with increased frailty... Reisinger KW, van Vugt JL, Tegels JJ, et al. Ann Surg 2015;261:345-52 Publication date: February 1, 2015 Summary This study was aimed at determining the association of sarcopenia with postoperative morbidity and mortality after colorectal surgery. A total of 310... Gale CR, Cooper C, Sayer AA Age Ageing 2015;44:162-165 Publication date: January 1, 2015 Summary In this study, the authors examined the prevalence of frailty and disability among 5,450 individuals aged 60 and over from the English Longitudinal Study of Ageing, as... Zisberg A, Shadmi E, Gur-Yaish N, Tonkikh O, Sinoff G J Am Geriatr Soc 2015;63:55-62 Publication date: January 1, 2015 Summary Hospitalizations often lead to functional loss in older people. There are many factors (e.g. patient characteristics) that may explain this... Romero-Ortuno R, Soraghan C BMJ Open 2014;4:e006645 Publication date: December 23, 2014 Summary The objective of the present study was to create and validate a frailty assessment tool for community-dwelling adults aged ≥75 years. It is a Longitudinal, population-based... Dapp U, Minder CE, Anders J, Golgert S, von Renteln-Kruse W BMC Geriatr 2014;14:141 Publication date: December 19, 2014 Summary The detection of functional decline in elderly persons is not an easy task. Dapp et al. suggest that the self-reporting Functional Ability... Mijnarends DM, Schols JM, Meijers JM, et al. J Am Med Dir Assoc 2014; Dec 17 [Epub ahead of print] Publication date: December 17, 2014 Summary Both sarcopenia and physical frailty are geriatric syndromes causing loss of functionality and independence. Mijnarends et... Syddall HE, Westbury LD, Cooper C, Sayer AA J Am Med Dir Assoc 2014; Dec 15 [Epub ahead of print] Publication date: December 15, 2014 Summary Walking speed is central to emerging consensus definitions of sarcopenia and frailty; it is also a major predictor of future... Kumar R, Mohan N, Upadhyay AD, et al. Aging Cell 2014;13:975-80 Publication date: December 1, 2014 Summary Manifestations of frailty include sarcopenia (loss of skeletal muscle mass), cognitive decline, abnormal functioning of immune and neuroendocrine systems, and... Forti P, Maioli F, Zagni E, et al. J Nutr Health Aging 2014;18:912-8 Publication date: December 1, 2014 Summary The objective of this study was to determine the usefulness of physical phenotype of frailty, cognitive impairment and serum albumin for risk stratification... Kim S, Park JL, Hwang HS, Kim YP Korean J Fam Med 2014;35:309-320 Publication date: November 1, 2014 Summary Frailty and cognitive impairment are considered the most common and yet the least well understood conditions in older adults. This study was conducted to... Romera L, Orfila F, Segura JM, et al. BMC Geriatr 2014;14:125 Publication date: November 27, 2014 Summary Frailty is a highly prevalent condition in old age leading to vulnerability and greater risk of adverse health outcomes and disability. Detecting and tackling... Robertson DA, Savva GM, Coen RF, Kenny RA J Am Geriatr Soc 2014;62:2118-2124 Publication date: November 1, 2014 Summary The objective of this study by Robertson et al. was to explore the relationship between cognitive function and frailty. Individuals aged 50 and... Oubaya N, Mahmoudi R, Jolly D, et al. J Nutr Health Aging 2014;18:757-64 Publication date: August 1, 2014 Summary The objective of this study by Oubaya et al. was to validate the modified version of the Short Emergency Geriatric Assessment (SEGAm) frailty instrument... Cesari M, Demougeot L, Boccalon H, et al. PLoS One 2014;9:e101745 Publication date: July 7, 2014 Summary The detection of frail older individuals living in the community represents a crucial preliminary step in the development of effective prevention against... Joseph B, Pandit V, Zangbar B, et al. J Am Coll Surg 2014;219:10-7.e1 Publication date: July 1, 2014 Summary Early prediction of discharge disposition is an important component in the management of trauma patients. The authors have previously demonstrated that frailty... Dent E, Chapman I, Howell S, Piantadosi C, Visvanathan R Age Ageing 2014;43:477-84 Publication date: July 1, 2014 Summary This is a prospective, observational study in patients aged ≥ 70 years admitted to a Geriatric Evaluation and Management Unit (GEMU) in Australia,... Kim SW, Han HS, Jung HW, et al. JAMA Surg 2014;149:633-40 Publication date: July 1, 2014 Summary The number of older patients who undergo surgery is increasing, and these patients often have comorbid conditions that may lead to postoperative mortality and morbidity.... Ferguson MK, Thompson K, Huisingh-Scheetz M, et al. PLoS One 2014;9:e98654 Publication date: June 3, 2014 Summary Frailty is a predictor of poor outcomes following many types of operations. Ferguson et al. measured thoracic surgeons’ accuracy in assessing... Lahousse L, Maes B, Ziere G, et al. Eur J Epidemiol 2014;29:419-27 Publication date: June 1, 2014 Summary Given the expanding elderly population and the major impact of population aging on health and social care, the identification of frail people among older adults... Wise BL, Parimi N, Zhang Y, et al. J Gerontol A Biol Sci Med Sci 2014;69:602-8. Publication date: May 1, 2014 Summary This is a longitudinal cohort study of men aged more than 65 years in the Osteoporotic Fractures in Men Study, examining the association of hip... Rojas-Fernandez CH, Patel T, Lee L Ann Pharmacother 2014;48:785-95 Publication date: June 1, 2014 Summary The purpose of this article is to describe the role of clinical pharmacists providing care to patients with cognitive complaints in a primary care-based,... Greene BR, Doheny EP, O’Halloran A, Anne Kenny R Age Ageing 2014;43:406-11 Publication date: May 1, 2014 Summary The concept of frailty in older adults has emerged as an important geriatric syndrome. It is a multi-factorial condition, influenced by the combination of... Tavassoli N, Guyonnet S, Abellan Van Kan G, et al. J Nutr Health Aging 2014;18:457-64 Publication date: May 1, 2014 Summary The authors report on the first two years of operation of the Geriatric Frailty Clinic for Assessment of Frailty and Prevention of Disability... Dorner TE, Luger E, Tschinderle J, et al. J Nutr Health Aging 2014;18:264-9 Publication date: March 1, 2014 Summary The authors explored the association between the impaired nutritional status and frailty in acute hospitalized elderly patients by using the MNA®-SF... Bagshaw SM, Stelfox HT, McDermid RC, et al. CMAJ 2014;186:E95-102 Publication date: February 4, 2014 Summary Frailty has not been evaluated in critically ill patients. The development of critical illness may lead to frailty in vulnerable patients, and critical illness... van Kempen JA, Schers HJ, Melis RJ, Olde Rikkert MG J Clin Epidemiol 2014;67:176-83. Publication date: February 1, 2014 Summary The EASY-Care Two-step Older persons Screening (EASY-Care TOS) tool is a practice-based tool designed to help family physicians identify... Gray SR, Da Boit M J Frailty Aging 2013;2:205-10 Publication date: December 1, 2013 Summary There are several nutritional strategies purported to be useful in the treatment of sarcopenia. In recent years, the n-3 polyunsaturated fatty acids (PUFAs) found in fish oil... Lacey LA, Niecko T, Leibman C, Liu E, Grundman M J Nutr Health Aging 2013;17:745-50. Publication date: November 1, 2013 Summary In patients with Alzheimer’s disease (AD), dependence has been shown to correlate with impairments in cognition, function and behaviour. In... Malmstrom TK, Morley JE J Nutr Health Aging 2013;17:723-5 Publication date: November 1, 2013 Summary In this editorial, the authors comment on a consensus statement published in the September 2013 of the Journal of Nutrition, Health & Aging. Physical frailty has... Cesari M, Andrieu S, Rolland Y, Nourhashemi F, Vellas B J Nutr Health Aging 2013;17:735-7 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of... Buchman AS, Bennett DA J Nutr Health Aging 2013;17:738-9 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of the Journal of Nutrition, Health... Woods AJ, Cohen RA, Pahor M J Nutr Health Aging 2013;17:741-3 Publication date: November 1, 2013 Summary The authors comment on the report of an international consensus conference on cognitive frailty published in the September 2013 of theJournal of Nutrition, Health... El-Khoury F, Cassou B, Charles MA, Dargent-Molina P BMJ 2013;347:f6234. Publication date: October 29, 2013 Summary Fall-related injuries are very common among older people and are a major cause of long-term pain and functional impairment. They also increase the risk... Hamaker ME, Jonker JM, de Rooij SE, Vos AG, Smorenburg CH, van Munster BC Lancet Oncol 2012;13:e437-44 Publication date: October 1, 2013 Summary In older patients with cancer, pre-screening may be used to identify fit patients who are able to receive standard... Harttgen K, Kowal P, Strulik H, Chatterji S, Vollmer S PLoS One 2013;8:e75847 Publication date: October 29, 2013 Summary Frailty is increasingly common as a result of population aging. Assessing levels of frailty in higher versus lower income countries gives a unique... Philp IJ Frailty Aging 2013;2:128 Publication date: September 1, 2013 Summary Primary care physicians are well aware of the human and financial consequences of frailty ‒ loss of independence in daily living activities, reduced participation in family and community... Metzelthin SF, van Rossum E, de Witte LP, et al. BMJ 2013;347:f5264. Publication date: September 12, 2013 Summary In this cluster randomized controlled trial, the authors randomly allocated 12 general practices in the Netherlands to a “Prevention of Care” approach or... Rowe JW, Fried LP J Frailty Aging 2013;2:126-7 Publication date: September 1, 2013 Summary In the context of a rapidly growing interest in frailty, the authors identify several valuable strategies for inclusion of special attention to the syndrome in the clinical care... Subra J, Gillette-Guyonnet S, Cesari M, Oustric S, Vellas B J Nutr Health Aging 2012;16:714-20. Publication date: August 1, 2013 Summary Despite growing importance placed on preventing disability, implementation of frailty parameters in the clinical setting is still... Cesari M, Vellas B, Gambassi G Exp Gerontol 2013;48:451-6 Publication date: April 1, 2013 Summary While biological and evolutionary ageing theories have been analysed for centuries, our current knowledge of how we age remains incomplete. In this article, the authors... Vellas B, Balardy L, Gillette-Guyonnet S, et al. J Nutr Health Aging 2013;17:629-31 Publication date: July 1, 2013 Summary Identification of frail patients before their vulnerability is made evident by the onset of a major clinical event is one of the major challenges... Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K Lancet 2013;381:752-62 Publication date: March 2, 2013 Summary The healthcare systems of today are characterized primarily by single-system illnesses, despite the fact that many elderly people have multi-organ... Malmstrom T, Morley J J Frailty Aging 2013;2:55-6 Publication date: March 1, 2013 Summary This article reports on a presentation by Malmstrom and Morley at the December 2012 meeting of the International Task Force on Sarcopenia in Orlando, Florida, USA. In their... Favela J, Castro LA, Franco-Marina F, et al. Clin Interv Aging 2013;8:85-95 Publication date: January 1, 2013 Summary The objective of this present study was to assess whether an intervention based on nurse home visits including alert buttons (NV+AB) is effective in... Calvani R, Miccheli A, Landi F, et al. J Frailty Aging 2013;2:38-53 Publication date: March 1, 2013 Summary Older age is linked with significant changes in body composition, the most notable of which is loss of skeletal muscle, or sarcopenia. Adults over 35 lose... Morley JE, Malmstrom TK, Miller DK J Nutr Health Aging 2012;16:601-8 Publication date: August 1, 2012 Summary The aim of this longitudinal study was to validate the 5-item FRAIL scale (fatigue, resistance, ambulation, illnesses, and loss of weight) in a representative... Cesari M, Fielding RA, Pahor M, et al. J Frailty Aging 2012;1:102-10 Publication date: September 1, 2012 Summary In this consensus document, the International Working Group on Sarcopenia discusses the current state of the art in the development of biomarkers to be... Implementing frailty into clinical practice: we cannot wait Vellas B, Cestac P, Moley JE J Nutr Health Aging 2012;16:599-600. Publication date: August 1, 2012 Summary Since the 1980s, geriatric medicine has expanded to the point that there are acute care units, mobile... Yamada M, Arai H, Yoshimura K, et al. J Frailty Aging 2012;1:64-70. Publication date: June 1, 2012 Summary Resistance and/or aerobic training have been shown to be important for the prevention and management of sarcopenia in older adults. Similarly, nutritional... Gait speed: a new “vital sign” for older persons in primary care Subra J, Rougé-Bugeat M-E, Balardy L, et al. J Frailty Aging 2012;1:90-91. Publication date: June 1, 2012 Summary The identification of frailty in clinical practice needs to be promoted, and... Gutiérrez-Robledo LM, Avila-Funes JA J Frailty Aging 2012;1:13-7 Publication date: March 1, 2012 Summary Research on the determinants of adult and old-adult health recognizes the need to incorporate earlier life circumstances, including education, economic status,... 