Mossello E, Profili F, Di Bari M, et al.

Age Ageing 2016; Mar 23 [Epub ahead of print]

Publication date: March 23, 2016 (Most recent version: June 22, 2016)


Identification of older individuals at risk for health-related adverse outcomes (HRAO) is necessary for population-based preventive interventions. The aim of this study was to improve a previously validated postal screening questionnaire for frailty in non-disabled older subjects and to test its prognostic validity in a vast sample of older community-dwellers.

The questionnaire was mailed to 17,273 subjects and the response rate was 55%. Among the first 1,037 responders without overt disability, the revised questionnaire was 75% sensitive and 69% specific for physical frailty phenotype (ROC 0.772). Non-disabled subjects who screened positive had a higher risk of hospitalization in comparison with those who screened negative and similar to non-responders. Risk of adverse outcome was highest among disabled subjects.

In summary, a simple questionnaire delivered by mail has good accuracy in detecting physical frailty phenotype in non-disabled older subjects and is able to predict hospitalization.


Journal Website